Quantitative analysis of orbital soft tissue for the detection of dysthyroid optic neuropathy in patients with thyroid-associated ophthalmopathy, based on three-dimensional cube fast spin-echo Flex
Quantitative MRI analysis using 3D Cube FSE-Flex reveals that enlargement and edema of orbital soft tissues-specifically EOMV and OF-WF-are significant risk factors for DON. The combination of these parameters provides a robust imaging biomarker for early identification of DON in TAO patients, with potential clinical utility in risk stratification and treatment planning.
Authors
- Ban Luo (ORCID: https://orcid.org/0000-0002-1257-2423)
- Yangyang Yin (ORCID: https://orcid.org/0000-0001-7317-160X)
- Yu Chen (ORCID: https://orcid.org/0000-0001-5863-7002)
- Yali Zhao (ORCID: https://orcid.org/0000-0003-4129-3068)
- Yanqiang Ma (ORCID: https://orcid.org/0000-0001-8758-5037)
- Linhan Zhai (ORCID: https://orcid.org/0000-0002-1821-7852)
- Qiuxia Wang (ORCID: https://orcid.org/0000-0003-3317-5643)
- Jing Zhang (ORCID: https://orcid.org/0000-0003-0947-3421)
- Weiqiang Liang
- Gang Yuan (ORCID: https://orcid.org/0000-0002-0605-1568)
Institutions
- Sir Run Run Shaw Hospital (CN)
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2025-11-21
- DOI
- https://doi.org/10.21037/qims-2025-935
- Primary Topic
- Ophthalmology and Eye Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00