Identifying risk factors for refractory tyrosine kinase inhibitor-induced interstitial lung disease in patients with non-small cell lung cancer

The mortality rate associated with refractory TKI-ILD is substantial. Dyspnea, LDH >420 U/L at TKI-ILD onset, and DAD radiographic pattern are independent risk factors that may aid in identifying refractory TKI-ILD cases.

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Publication Details

Journal
Chinese Clinical Oncology
Published
2025-11-21
DOI
https://doi.org/10.21037/cco-25-56
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Identifying risk factors for refractory tyrosine kinase inhibitor-induced interstitial lung disease in patients with non-small cell lung cancer

Minmin Huang, Peixin Tan, Shasha Du, Wei Huang et al.
Chinese Clinical Oncology
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Identifying risk factors for refractory tyrosine kinase inhibitor-induced interstitial lung disease in patients with non-small cell lung cancer

Minmin Huang, Peixin Tan, Shasha Du, Wei Huang, H. Ye, Yanlin Zhu
article en

Abstract

The mortality rate associated with refractory TKI-ILD is substantial. Dyspnea, LDH >420 U/L at TKI-ILD onset, and DAD radiographic pattern are independent risk factors that may aid in identifying refractory TKI-ILD cases.

Chinese Clinical OncologyVol. 14(6)
Guangdong Academy of Medical Sciences (CN)
Openalex Percentile: Top 49%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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