Molecular mechanism of obesity-related left ventricular systolic dysfunction in mice and application of ultrasonic strain detection technology
The strain technique detected changes in myocardial systolic function earlier than the left ventricular ejection fraction (LVEF) in the obese mice. Left ventricular remodeling and a NLRP3-mediated inflammatory response occur in obese mice.
Authors
- Jing Xu (ORCID: https://orcid.org/0000-0003-0388-5046)
- Tomasz Kamil Urbanowicz (ORCID: https://orcid.org/0000-0001-8080-2764)
- Na Gao (ORCID: https://orcid.org/0000-0002-1831-8354)
- Xin Ma (ORCID: https://orcid.org/0000-0002-9325-6384)
- Dhruv Nayyar (ORCID: https://orcid.org/0000-0002-6590-3628)
- Fuxin Wan (ORCID: https://orcid.org/0000-0003-3699-2876)
- Qin Wang (ORCID: https://orcid.org/0009-0004-3954-7879)
Institutions
- Poznan University of Medical Sciences (PL)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2025-11-01
- DOI
- https://doi.org/10.21037/jtd-24-340
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00