Kupffer phase echo level ratio in contrast-enhanced ultrasound for differentiating malignant liver tumors
Kupffer phase quantification using the ELR provides a reproducible parameter for distinguishing HCC from other malignant liver tumors. Although sensitivity is modest, ELR offers high specificity, and its combination with vascular phase CEUS parameters significantly improves overall diagnostic accuracy. This supports the integration of ELR into CEUS workflows for more confident noninvasive liver tumor characterization.
Authors
- Huabin Zhang (ORCID: https://orcid.org/0009-0005-8124-8036)
- Xia Xie (ORCID: https://orcid.org/0009-0001-3996-2456)
- Lei Zhang (ORCID: https://orcid.org/0000-0001-8118-1402)
- Zheyuan Zhang (ORCID: https://orcid.org/0000-0003-1868-9240)
- Zhi-Yong Bai (ORCID: https://orcid.org/0000-0003-2947-5512)
- Qingting Tan
- Xiuming Wang (ORCID: https://orcid.org/0000-0002-1026-8815)
Institutions
- Beijing Tsinghua Chang Gung Hospital (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2025-11-21
- DOI
- https://doi.org/10.21037/qims-2025-1229
- Primary Topic
- Ultrasound Imaging and Elastography
- Type
- article
- Field-Weighted Citation Impact
- 0.00