Impaired glymphatic system for upper limb motor dysfunction in patients with acute ischemic stroke

Our findings suggest that a decreased ALPS index in AIS patients with upper limb motor dysfunction indicates impaired glymphatic function. Moreover, the level of the ALPS index is associated with the severity of stroke. ALPS index could be a potential neuroimaging biomarker for AIS patients with upper limb motor dysfunction.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2025-11-21
DOI
https://doi.org/10.21037/qims-2025-1170
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00
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article

Impaired glymphatic system for upper limb motor dysfunction in patients with acute ischemic stroke

Yaodan Zhang, Ling Zhao, Zihan Yin, Lichuan Zeng et al.
Quantitative Imaging in Medicine and Surgery
Cerebrospinal fluid and hydrocephalus
article

Impaired glymphatic system for upper limb motor dysfunction in patients with acute ischemic stroke

Yaodan Zhang, Ling Zhao, Zihan Yin, Lichuan Zeng, Mingguo Xie, Wang Xiao, Wei Li, Wenbin Wu
article en

Abstract

Our findings suggest that a decreased ALPS index in AIS patients with upper limb motor dysfunction indicates impaired glymphatic function. Moreover, the level of the ALPS index is associated with the severity of stroke. ALPS index could be a potential neuroimaging biomarker for AIS patients with upper limb motor dysfunction.

Quantitative Imaging in Medicine and SurgeryVol. 15(12)
Shanghai University of Traditional Chinese Medicine (CN), Yueyang Hospital (CN), Anyang Hospital of Traditional Chinese Medicine (CN), Chengdu University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 61%
Cerebrospinal fluid and hydrocephalus
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