A National Audit of Current UK Practice on the Use of Anti‐Emetics for Chemotherapy‐Induced Nausea and Vomiting in Children

This UK national audit aimed to assess adherence to evidence-based chemotherapy-induced nausea and vomiting (CINV) guidelines for children with cancer, which emphasise treatment emetogenicity assessment, symptom monitoring and appropriate antiemetic use. Data from 99 inpatient episodes in 12 centres were collected over 5 days in January 2024 via an anonymised survey. Concordance with 2018 CCLG guidelines was 83%, with 6% of cases overestimated and 11% underestimated levels of emetogenicity. This first UK national audit demonstrates generally good alignment with guidelines. Future audits should include prescribing practices in outpatient and ambulatory settings to provide a more comprehensive evaluation of CINV management.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-11-20
DOI
https://doi.org/10.1002/mpo.70013
Primary Topic
Nausea and vomiting management
Type
article
Field-Weighted Citation Impact
0.00

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article

A National Audit of Current UK Practice on the Use of Anti‐Emetics for Chemotherapy‐Induced Nausea and Vomiting in Children

Jessica E. Morgan, Jessica Bate, Thomas J. Jackson, Bob Phillips et al.
Pediatric Blood & Cancer
Nausea and vomiting management
article

A National Audit of Current UK Practice on the Use of Anti‐Emetics for Chemotherapy‐Induced Nausea and Vomiting in Children

Jessica E. Morgan, Jessica Bate, Thomas J. Jackson, Bob Phillips, Eloise Neumann
article en

Abstract

This UK national audit aimed to assess adherence to evidence-based chemotherapy-induced nausea and vomiting (CINV) guidelines for children with cancer, which emphasise treatment emetogenicity assessment, symptom monitoring and appropriate antiemetic use. Data from 99 inpatient episodes in 12 centres were collected over 5 days in January 2024 via an anonymised survey. Concordance with 2018 CCLG guidelines was 83%, with 6% of cases overestimated and 11% underestimated levels of emetogenicity. This first UK national audit demonstrates generally good alignment with guidelines. Future audits should include prescribing practices in outpatient and ambulatory settings to provide a more comprehensive evaluation of CINV management.

Pediatric Blood & CancerVol. 73(2)
Leeds Teaching Hospitals NHS Trust (GB), Great Ormond Street Hospital (GB), Birmingham Children's Hospital (GB), Southampton Children's Hospital (GB), University College London (GB), University of York (GB)
Alder Hey Children's NHS Foundation Trust, University College London, Sheffield Children's NHS Foundation Trust
Openalex Percentile: Top 46%
Nausea and vomiting management
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