Equity of Access to Disease-Modifying Therapy for Pediatric Multiple Sclerosis: A Survey of Canadian Prescribers

A perceived barrier to effective treatment of pediatric-onset multiple sclerosis (POMS) is access to disease-modifying therapies (DMTs). An online Canada-wide survey of POMS DMT prescribers was used to identify patterns in, and barriers to, DMT access. Nineteen prescribers provided responses. Overall, DMT access via private versus government drug plans was variable. First-generation (e.g., beta-interferon) DMTs were more accessible via government plans versus second-generation DMTs (e.g., ocrelizumab). Most DMTs were available through private insurance plans. B-cell depleting therapies were the most difficult to access. Variability in DMT access for POMS raises concerns about health equity and care optimization.

Authors

Institutions

Publication Details

Journal
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Published
2025-11-21
DOI
https://doi.org/10.1017/cjn.2025.10479
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Equity of Access to Disease-Modifying Therapy for Pediatric Multiple Sclerosis: A Survey of Canadian Prescribers

Penelope Smyth, Joley Johnstone, Helen Tremlett, Mark D. Eisner et al.
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Multiple Sclerosis Research Studies
article

Equity of Access to Disease-Modifying Therapy for Pediatric Multiple Sclerosis: A Survey of Canadian Prescribers

Penelope Smyth, Joley Johnstone, Helen Tremlett, Mark D. Eisner, E. Ann Yeh, Lauren Strasser, Beyza Çiftçi, Judith Glennie
article en

Abstract

A perceived barrier to effective treatment of pediatric-onset multiple sclerosis (POMS) is access to disease-modifying therapies (DMTs). An online Canada-wide survey of POMS DMT prescribers was used to identify patterns in, and barriers to, DMT access. Nineteen prescribers provided responses. Overall, DMT access via private versus government drug plans was variable. First-generation (e.g., beta-interferon) DMTs were more accessible via government plans versus second-generation DMTs (e.g., ocrelizumab). Most DMTs were available through private insurance plans. B-cell depleting therapies were the most difficult to access. Variability in DMT access for POMS raises concerns about health equity and care optimization.

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
University of British Columbia (CA), University of Alberta (CA), London Health Sciences Centre (CA), Hospital for Sick Children (CA), LEK Consulting (United States) (US)
Openalex Percentile: Top 51%
Multiple Sclerosis Research Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Equity of Access to Disease-Modifying Therapy for Pediatric Multiple Sclerosis: A Survey of Canadian Prescribers — Penelope Smyth, Joley Johnstone, et al. · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques (2025) | TGRS Research Map | TGRS