Optimized multi-epitope neoantigen human cytomegalovirus vaccine based on adenovirus vectors elicits potent antiviral immunity
We have developed a novel multi-epitope recombinant adenovirus vaccine that can elicit long-lasting antiviral cellular immunity, providing new insights into the development of vaccines against HCMV.
Authors
- Fengjun Liu
- Zonghui Li (ORCID: https://orcid.org/0000-0002-0772-1738)
- Xianjuan Zhang (ORCID: https://orcid.org/0000-0003-0585-4438)
- Shasha Jiang
- Yan Yu (ORCID: https://orcid.org/0000-0002-5478-1733)
- Yiran Zhang (ORCID: https://orcid.org/0000-0002-9554-6078)
- Bin Wang (ORCID: https://orcid.org/0000-0003-1971-1972)
- Yi Zhang (ORCID: https://orcid.org/0000-0002-6375-1712)
- Yunyang Wang (ORCID: https://orcid.org/0000-0002-2894-4527)
- Wenxuan Liu (ORCID: https://orcid.org/0000-0002-8459-0241)
- Jing Lv (ORCID: https://orcid.org/0000-0002-5048-3982)
- Heping Zhao (ORCID: https://orcid.org/0000-0002-7896-6636)
- Xiaoli Yang (ORCID: https://orcid.org/0000-0002-7291-5117)
Institutions
- Qingdao University (CN)
- Wuhan University (CN)
- Xi'an Honghui Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
- Wuhan Asia Heart Hospital (CN)
- Wuhan Union Hospital (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/fimmu.2025.1658220
- Citations
- 1
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 1.35