Preclinical pharmacokinetic characterization of (R)-ketamine injection, a novel antidepressant glutamatergic agent
The preclinical pharmacokinetic characteristics of (R)-ketamine injection have been thoroughly investigated, and these findings can provide valuable information for predicting the first-in-human dose and designing Phase I clinical trials for (R)-ketamine injection.
Authors
- Li Ding (ORCID: https://orcid.org/0000-0002-0967-7021)
- Bingjie Zou (ORCID: https://orcid.org/0000-0003-1056-9156)
- Rui Wang (ORCID: https://orcid.org/0000-0003-2782-7772)
- Yongchao Jin (ORCID: https://orcid.org/0000-0002-9475-8300)
Institutions
- China Pharmaceutical University (CN)
- Nanjing Institute of Technology (CN)
- Jiangsu Nhwa Pharmaceutical (China) (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/fphar.2025.1699304
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00