Shared diagnostic genes and potential mechanism between allergic rhinitis and atopic dermatitis revealed by integrated transcriptomic analysis and machine learning
AR and AD share a common molecular landscape, and the five hub genes identified here represent robust biomarkers for diagnosis and potential therapeutic targets for these interconnected diseases.
Authors
- Liang Xu (ORCID: https://orcid.org/0000-0003-4238-9061)
- Junjie Bi (ORCID: https://orcid.org/0000-0002-7298-6476)
- Xiangjing Chen
- Wei Meng (ORCID: https://orcid.org/0000-0003-1268-9397)
- Ying Zhang (ORCID: https://orcid.org/0000-0002-8828-0873)
- Meng Sun (ORCID: https://orcid.org/0000-0002-1756-3542)
- Jia Yuan (ORCID: https://orcid.org/0000-0001-5544-1768)
- Yao Lei (ORCID: https://orcid.org/0000-0002-4299-8011)
- Boming Zhang (ORCID: https://orcid.org/0000-0003-4430-3997)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Jinan Central Hospital (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Allergy
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/falgy.2025.1686370
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China