THBS1 as a candidate biomarker and fibrotic mediator in radiation-induced liver injury: insights from TMT-labeled quantitative proteomics
This study provides new insights into the pathogenesis of RILI, and identifies THBS1 as a potential biomarker for RILI diagnosis and monitoring.
Authors
- Haixu Wang (ORCID: https://orcid.org/0009-0000-4848-4890)
- Yue Deng
- Ying Yan (ORCID: https://orcid.org/0000-0002-3546-3991)
- Jing Liu (ORCID: https://orcid.org/0000-0002-3311-0818)
- Defu Yang (ORCID: https://orcid.org/0000-0002-0212-9882)
- Tong Wu (ORCID: https://orcid.org/0009-0004-5980-7754)
- Ying Xu (ORCID: https://orcid.org/0000-0001-7341-8676)
- Haibo Zhang (ORCID: https://orcid.org/0000-0002-5134-4167)
- Tingting Wang (ORCID: https://orcid.org/0000-0001-6983-6314)
- Ying Sun
- Zixi Wang (ORCID: https://orcid.org/0000-0003-0225-5202)
- Feng Shang (ORCID: https://orcid.org/0000-0003-1630-4044)
- Xue Ren
- Dongyang Lv
Institutions
- Second Military Medical University (CN)
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- General Hospital of Shenyang Military Region (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
- Liaoning Cancer Hospital & Institute (CN)
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/fphar.2025.1659870
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China