Comparative evaluation of two DNA methylation assays for triage of hrHPV E6/E7 mRNA–positive women
Overall, although limited by its single-center design and modest sample size, GynTect<sup>®</sup> and CISCER<sup>®</sup> demonstrated comparable clinical performance for the identification of high-grade CIN in hrHPV E6/E7 mRNA-positive women, supporting their potential role as effective triage tools in HPV-based cervical cancer screening.
Authors
- Qiuxia Yang (ORCID: https://orcid.org/0000-0002-2852-3925)
- Shuyu Lai (ORCID: https://orcid.org/0000-0003-3343-7463)
- Jie Teng (ORCID: https://orcid.org/0000-0002-6534-8601)
- Chang Li (ORCID: https://orcid.org/0000-0002-7857-1028)
- Guanglu Che (ORCID: https://orcid.org/0000-0002-4051-583X)
- Fang Liu (ORCID: https://orcid.org/0000-0003-4841-8206)
- Hui Jian (ORCID: https://orcid.org/0000-0003-3057-1253)
- Jiaxin Duan (ORCID: https://orcid.org/0000-0002-2371-1927)
- Yongmei Jiang (ORCID: https://orcid.org/0000-0003-0703-453X)
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/fpubh.2025.1723553
- Citations
- 1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Sichuan University
- National Key Research and Development Program of China