Medical cannabis utilization in children – a study based on a nationwide cohort
Our findings suggest that short-term persistence of medical cannabis therapy is lower in children compared to adolescents and young adults. Moreover, many pediatric patients required adjustments to their THC ratios and showed a high frequency of treatment discontinuation. These observations underscore the importance of targeted strategies to improve medical cannabis treatment effectiveness and adherence in the pediatric population. Although MC may offer therapeutic benefits for pediatric patients, our findings emphasize the importance of careful patient selection and close medical follow-up to optimize clinical outcomes.
Authors
- Noa Yakirevich-Amir
- Omer B. Bonne (ORCID: https://orcid.org/0000-0002-0891-7046)
- Maya Berlin (ORCID: https://orcid.org/0000-0003-4731-742X)
- Ariela Hazan (ORCID: https://orcid.org/0009-0007-6125-2868)
- Elkana Kohn (ORCID: https://orcid.org/0000-0003-0197-4440)
- Orit Stolar (ORCID: https://orcid.org/0000-0001-7071-5683)
- Matitiahu Berkovitch (ORCID: https://orcid.org/0000-0001-9579-383X)
- Ilan Matok (ORCID: https://orcid.org/0000-0003-1559-9258)
- Karel Allegaert (ORCID: https://orcid.org/0000-0001-9921-5105)
- Nir Treves (ORCID: https://orcid.org/0000-0002-8525-5840)
- Elyad M. Davidson
- John N. van den Anker
Institutions
- Children's National (US)
- Tel Aviv University (IL)
- George Washington University (US)
- Hebrew University of Jerusalem (IL)
- Rega Institute for Medical Research (BE)
- Hadassah Medical Center (IL)
- Jerusalem Institute for Israel Studies (IL)
- Erasmus MC (NL)
- Maccabi Healthcare Services (IL)
- Assaf Harofeh Medical Center (IL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/fphar.2025.1646560
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00