Safe General Anesthesia in a Pediatric Patient With <scp>1p36.33</scp> Duplication Syndrome: A Rare Case Report

1p36.33 Duplication Syndrome is an extremely rare autosomal dominant multi-gene disorder, including the disruption of the ATAD3 gene cluster, which encodes for mitochondrial membrane proteins. As of 2025, there is only one publicly available article highlighting the characteristic findings in patients with this condition; however, there is no existing data on safe anesthetic management. We present a case highlighting the successful and uneventful care of a pediatric patient with this condition.

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Publication Details

Journal
Clinical Case Reports
Published
2025-11-01
DOI
https://doi.org/10.1002/ccr3.71476
Primary Topic
Genomic variations and chromosomal abnormalities
Type
article
Field-Weighted Citation Impact
0.00
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article

Safe General Anesthesia in a Pediatric Patient With 1p36.33 Duplication Syndrome: A Rare Case Report

Esha Thakkar, Michael M. McNally, Adrienne Hutton
Clinical Case Reports
Genomic variations and chromosomal abnormalities
article

Safe General Anesthesia in a Pediatric Patient With 1p36.33 Duplication Syndrome: A Rare Case Report

Esha Thakkar, Michael M. McNally, Adrienne Hutton
article en

Abstract

1p36.33 Duplication Syndrome is an extremely rare autosomal dominant multi-gene disorder, including the disruption of the ATAD3 gene cluster, which encodes for mitochondrial membrane proteins. As of 2025, there is only one publicly available article highlighting the characteristic findings in patients with this condition; however, there is no existing data on safe anesthetic management. We present a case highlighting the successful and uneventful care of a pediatric patient with this condition.

Clinical Case ReportsVol. 13(11)
East Carolina University (US)
Openalex Percentile: Top 62%
Genomic variations and chromosomal abnormalities
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