Identification of an Exosomal miRNA Signature in Newly Diagnosed Essential Hypertensive Adults
This study identified a unique hypertensive exosomal miRNA profile when used combination with BMI. The miRNA signature provided insights into the mechanisms involved in the early stages of hypertension and offers leads for further validation in biomarker discovery to alleviate the burden of cardiovascular diseases.
Authors
- Teck Yew Low (ORCID: https://orcid.org/0000-0001-7878-7534)
- William M. Chilian (ORCID: https://orcid.org/0000-0003-4522-7914)
- Paulina Pei Suu Tan
- Yuh Fen Pung (ORCID: https://orcid.org/0000-0001-6195-3970)
- Yook Chin Chia (ORCID: https://orcid.org/0000-0003-1995-0359)
- Hooi Min Lim (ORCID: https://orcid.org/0000-0003-2481-9363)
- Shamsul Mohd Zain (ORCID: https://orcid.org/0000-0002-3441-6659)
- Tengku Rogayah Tengku Abd Rashid
- Navin Kumar Devaraj (ORCID: https://orcid.org/0000-0002-9081-2162)
- Nur Afrina Muhamad Hendri
- Siew Mooi Ching
- Yong Ling Sou
Institutions
- Ministry of Health (MY)
- Universiti Putra Malaysia (MY)
- University of Nottingham Malaysia Campus (MY)
- University of Malaya (MY)
- Sunway University (MY)
- Northeast Ohio Medical University (US)
Publication Details
- Journal
- British Journal of Biomedical Science
- Published
- 2025-11-21
- DOI
- https://doi.org/10.3389/bjbs.2025.14780
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00