MCPyV small T antigen enhances HPV16 oncogene expression, promotes Ca Ski cell proliferation, and reduces 5-fluorouracil-induced apoptosis in cervical cancer cells
These findings underscore the potential cooperative effects of viral oncoproteins from distinct viruses in driving therapeutic resistance, highlighting the need for further research into their molecular interactions to inform targeted cervical cancer treatments.
Authors
- Leila Kohan (ORCID: https://orcid.org/0000-0001-7124-2849)
- Mohammad Kargar (ORCID: https://orcid.org/0000-0002-9531-3645)
- Ali Farhadi (ORCID: https://orcid.org/0000-0002-2271-670X)
- Tahereh Pakdel
- Mahdokht Hossein Aghdaei (ORCID: https://orcid.org/0000-0003-2354-8813)
Institutions
- Shiraz University of Medical Sciences (IR)
- Sadra Institute Of Higher Education (IR)
- Islamic Azad University of Arsanjan (IR)
- Islamic Azad University of Shiraz (IR)
Publication Details
- Journal
- Infectious Medicine
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.imj.2025.100222
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00