CAF derived IL-33 mediated EMT to promote the metastasis of LSCC cells
IL-33 derived from CAFs mediates EMT to promote the metastasis of LSCC cells. The findings of our study not only provide a new mechanism for the activation of CAFs and the metastasis of LSCC but also offer theoretical significance and application value for more effective prevention and treatment strategies in clinical practice.
Authors
- Shuixian Huang (ORCID: https://orcid.org/0000-0002-0381-8508)
- Shiyan Chen
- Jieyu Zhou (ORCID: https://orcid.org/0000-0002-5647-2950)
- Liyun Yang (ORCID: https://orcid.org/0000-0001-8429-7187)
- Yanmei Wang
Institutions
- Qingdao University (CN)
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Ninth People's Hospital (CN)
- People's Liberation Army No. 150 Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
- Shanghai Pudong New Area Gongli Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1186/s40001-025-03431-4
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- Natural Science Foundation of Fujian Province