Biomarkers of endothelial damage in erectile dysfunction based on preclinical studies: a systematic review
eNOS; VEGF; nNOS; aSMA; LncRNA; and Hebp1 showed decreased expression in the presence of endothelial damage, while FACL-4; PACS-2; IP3R1; endocan; endothelial microparticles; and endothelial progenitor cells showed an increase under the same conditions. These could become markers with implications for clinical trials and the development of new targeted treatments for ED.
Authors
- Herney Andrés García‐Perdomo (ORCID: https://orcid.org/0000-0001-6945-8261)
- María Paula Gómez-Bueno
- Marcelo Marconi
Institutions
- Pontificia Universidad Católica de Chile (CL)
- Universidad del Valle (CO)
Publication Details
- Journal
- International Urology and Nephrology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1007/s11255-025-04895-3
- Primary Topic
- Sexual function and dysfunction studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00