Ultrasound-detected crystal depositions and clinical flares dissolve during successful urate-lowering therapy: 5-year follow-up results from the treat-to-target NOR-Gout study
Five years of T2T-ULT resulted in most patients achieving sUA target, reduction of crystal depositions, and dissolution of double contour and tophi in most patients. Only a few patients experienced flares, and they had higher levels of sUA and crystal depositions, supporting the importance of keeping sUA low.
Authors
- Hilde Berner Hammer (ORCID: https://orcid.org/0000-0001-7317-8991)
- Till Uhlig (ORCID: https://orcid.org/0000-0002-6881-9552)
- Lene Terslev (ORCID: https://orcid.org/0000-0001-8193-9471)
- Espen A Haavardsholm (ORCID: https://orcid.org/0000-0002-5893-1698)
- Lars Fridtjof Karoliussen
Institutions
- Glostrup Hospital (DK)
- Copenhagen University Hospital (DK)
- Diakonhjemmet Hospital (NO)
Publication Details
- Journal
- Annals of the Rheumatic Diseases
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.ard.2025.10.029
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00