The mechanisms of kidney–lung interactions in chronic kidney disease-associated pulmonary diseases: A two-sample Mendelian randomization study
Predicted CKD was positively associated with the increased risk of asthma, pneumonia, ARDS, and COPD. Furthermore, interleukin-1β and tumor necrosis-α, 25-hydroxyvitamin D and PTH mediated the kidney-lung interactions in CKD-associated pulmonary diseases.
Authors
- Shengyi Yang (ORCID: https://orcid.org/0000-0002-5841-4674)
- Yulu He (ORCID: https://orcid.org/0000-0002-2531-1521)
- Qun Lu (ORCID: https://orcid.org/0000-0002-6211-6565)
- Liyuan Sun (ORCID: https://orcid.org/0000-0003-2043-2911)
- Zhenwei Li (ORCID: https://orcid.org/0009-0006-2466-5420)
- Changxian Wang
Institutions
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1080/0886022x.2025.2578837
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00