Pediatric Massive Transfusion Protocol: A Narrative Review and Proposed Algorithm

Hemorrhage is the leading cause of preventable death in the United States and carries a disproportionately high mortality in pediatric patients. However, the literature surrounding pediatric trauma resuscitation, specifically massive transfusion protocol (MTP), is less robust than for adults. In this review, we assess the current state of the literature surrounding pediatric MTP (pMTP). Content experts in the field of trauma and pediatric surgery developed an algorithm to be used to identify cases requiring activation pMTP until a definitive scoring system that is both reliable and validated is created.

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Publication Details

Journal
The American Surgeon
Published
2025-11-20
DOI
https://doi.org/10.1177/00031348251400195
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
Field-Weighted Citation Impact
0.00
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article

Pediatric Massive Transfusion Protocol: A Narrative Review and Proposed Algorithm

Michaela Forgione, Nicholas James Larson, David J. Dries, Uroghupatei P. Iyegha et al.
The American Surgeon
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

Pediatric Massive Transfusion Protocol: A Narrative Review and Proposed Algorithm

Michaela Forgione, Nicholas James Larson, David J. Dries, Uroghupatei P. Iyegha, Amelia T. Collings, Frederick Bolles Rogers, Benoît Blondeau, Barbara A. Gaines
article en

Abstract

Hemorrhage is the leading cause of preventable death in the United States and carries a disproportionately high mortality in pediatric patients. However, the literature surrounding pediatric trauma resuscitation, specifically massive transfusion protocol (MTP), is less robust than for adults. In this review, we assess the current state of the literature surrounding pediatric MTP (pMTP). Content experts in the field of trauma and pediatric surgery developed an algorithm to be used to identify cases requiring activation pMTP until a definitive scoring system that is both reliable and validated is created.

The American SurgeonVol. 92(4)
Regions Hospital (US), Synod Hospital (IN), Presbyterian Hospital (US), Southwestern Medical Center (US), UPMC Presbyterian (US), Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 58%
Trauma, Hemostasis, Coagulopathy, Resuscitation
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