Associations of long-term cumulative C-reactive protein and glycoprotein acetyls concentrations in childhood, adolescence and adulthood with adulthood retinal microvascular structure
Long-term cumulative hsCRP exposure was associated with wider venules in young and mid-adulthood, whereas the associations with venular tortuosity were inconsistent. Wider retinal venules might act as a marker for cumulative inflammatory burden.
Authors
- Hanna Vaahtoranta‐Lehtonen
- Markus Juonala (ORCID: https://orcid.org/0000-0001-9498-364X)
- Carol Y. Cheung (ORCID: https://orcid.org/0000-0002-9672-1819)
- Juha Mykkänen (ORCID: https://orcid.org/0000-0001-9898-2660)
- Antti Jula (ORCID: https://orcid.org/0000-0002-3522-5301)
- Tapani Rönnemaa (ORCID: https://orcid.org/0000-0001-7440-2828)
- Mika A. P. Kähönen (ORCID: https://orcid.org/0000-0002-4510-7341)
- Jaakko Nevalainen (ORCID: https://orcid.org/0000-0001-6295-0245)
- Harri Niinikoski (ORCID: https://orcid.org/0000-0002-7071-918X)
- Oskari Repo (ORCID: https://orcid.org/0000-0002-9005-7806)
- Suvi Rovio (ORCID: https://orcid.org/0000-0003-0911-7478)
- Tomi P Laitinen (ORCID: https://orcid.org/0000-0003-3553-9957)
- Jorma S.A. Viikari (ORCID: https://orcid.org/0000-0001-6452-010X)
- Robyn J. Tapp (ORCID: https://orcid.org/0000-0002-8553-2684)
- Mika Ala‐Korpela (ORCID: https://orcid.org/0000-0001-5905-1206)
- Katja Pahkala (ORCID: https://orcid.org/0000-0001-9338-4397)
- Terho J. Lehtimäki (ORCID: https://orcid.org/0000-0002-2555-4427)
- Olli T. Raitakari
Institutions
- Tampere University (FI)
- University of Eastern Finland (FI)
- Chinese University of Hong Kong (HK)
- Turku University Hospital (FI)
- Finnish Institute for Health and Welfare (FI)
- Kuopio University Hospital (FI)
- Tampere University Hospital (FI)
- Tampere University (FI)
- Fimlab (Finland) (FI)
- Melbourne Health (AU)
- Coventry University (GB)
- University of Oulu (FI)
Publication Details
- Journal
- Atherosclerosis
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.atherosclerosis.2025.120595
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Foundation for Cardiovascular Research
- Suomen Lääketieteen Säätiö
- Yrjö Jahnssonin Säätiö
- Kela
- Suomen Kulttuurirahasto
- Juho Vainion Säätiö
- Signe ja Ane Gyllenbergin Säätiö
- Emil Aaltosen Säätiö
- Sydäntutkimussäätiö
- Sigrid Juséliuksen Säätiö
- Tampereen Tuberkuloosisäätiö
- Diabetesliitto
- Paavo Nurmen Säätiö
- Tays
- Turun Yliopistollinen Keskussairaala
- Turun Yliopistosäätiö