Autonomic dysfunction and vasoregulation in long COVID-19 are linked to anti-GPCR autoantibodies
These findings suggest that AABs play a modulatory role in sympathetic nervous system-mediated regulation of cardiac rhythm and vascular function in PCS. AAB levels did not correlate with BCR and TCR repertoire metrics or T-cell receptor beta variable gene usage.
Authors
- Frank C. Mooren (ORCID: https://orcid.org/0000-0002-0258-2732)
- Kai Schulze‐Forster (ORCID: https://orcid.org/0009-0008-7297-8717)
- Gabriela Riemekasten (ORCID: https://orcid.org/0000-0002-5406-2464)
- Shambhabi Chatterjee (ORCID: https://orcid.org/0000-0001-5978-3562)
- Hendrik Schäfer (ORCID: https://orcid.org/0000-0001-8598-9003)
- Boris Schmitz (ORCID: https://orcid.org/0000-0001-7041-7424)
- Christoph Schultheiß (ORCID: https://orcid.org/0000-0001-9789-5776)
- Mascha Binder (ORCID: https://orcid.org/0000-0003-0663-3004)
- René Garbsch (ORCID: https://orcid.org/0000-0001-7428-5692)
- Christian v. Bar (ORCID: https://orcid.org/0000-0002-1239-5105)
- Harald Heidecke (ORCID: https://orcid.org/0009-0009-1270-202X)
Institutions
- Witten/Herdecke University (DE)
- University Hospital of Basel (CH)
- Institute of Pathology Celle (DE)
- Universitäres Kinderwunschzentrum Lübeck (DE)
- Fraunhofer Institute for Toxicology and Experimental Medicine (DE)
- University Hospital Schleswig-Holstein (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.jaci.2025.10.034
- Citations
- 2
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 2.78