Correlation between anti-Müllerian hormone, hypertension and vascular age: the Generation R Study, a population-based prospective cohort study
This large prospective cohort study shows that low AMH levels later in life, independent of age, are associated with hypertension. The results indicate that diminished ovarian reserve at a younger age is associated with indicators of vascular alterations. Women with low AMH levels should not only be counseled about potential fertility issues, but should also be informed about their increased risk of vascular damage in order to take appropriate preventive measures. In the future, AMH may serve as a prospective marker for the early detection of cardiovascular diseases.
Authors
- Elisabeth J. Vinke (ORCID: https://orcid.org/0000-0002-7395-0723)
- EAP Steegers
- Joop S.E. Laven (ORCID: https://orcid.org/0000-0002-5444-9845)
- Sarah Schalekamp–Timmermans (ORCID: https://orcid.org/0000-0001-6647-6501)
- Sjoerd A.A. van den Berg (ORCID: https://orcid.org/0000-0001-5937-7505)
- Y V Louwers
- Ramon Dykgraaf (ORCID: https://orcid.org/0000-0003-1519-4285)
Institutions
- Erasmus MC (NL)
Publication Details
- Journal
- Maturitas
- Published
- 2025-11-21
- DOI
- https://doi.org/10.1016/j.maturitas.2025.108785
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00