Rhodium-catalyzed C–H Annulation of Aldonitrones with Allyl Methyl Carbonate
Abstract The Rh(III)-catalyzed, nitrone-directed C–H activation/allylation/1,3-dipolar cycloaddition sequence with C-aryl-N-tert-butyl nitrones and allyl methyl carbonate gives polycyclic isoxazolidines, in many cases with high or complete regioselectivity for products with a condensed ring system (containing a 1-amino-2-hydroxymethyl-indane skeleton).
Authors
- Sylwia Ostrowska (ORCID: https://orcid.org/0000-0002-4174-6517)
- Rafał Loska (ORCID: https://orcid.org/0000-0002-0823-4675)
- Barbara Stańska
Institutions
- Institute of Organic Chemistry (PL)
- Adam Mickiewicz University in Poznań (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Synlett
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1055/a-2752-7699
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94