The obesity and lipid paradoxes in chronic kidney disease: mechanisms, interventions, and future directions
The obesity and lipid paradoxes in CKD are not merely anomalies nor statistical fallacies to be adjusted for, but manifestations of CKD's distinct metabolic milieu. Their recognition highlights the need for individualized approaches beyond conventional risk factor modification. By integrating assessment of body composition, nutrition, and inflammation, precision nephrology can provide tailored interventions that improve prognosis.
Authors
- Yoshitsugu Obi (ORCID: https://orcid.org/0000-0001-7032-4383)
- Rina Takahashi (ORCID: https://orcid.org/0000-0002-5845-3243)
- Csaba Pal Kovesdy (ORCID: https://orcid.org/0000-0002-8204-911X)
Institutions
- Los Angeles County Department of Health Services (US)
- University of Tennessee Health Science Center (US)
- GTx (United States) (US)
- University of Mississippi Medical Center (US)
Publication Details
- Journal
- Current Opinion in Nephrology & Hypertension
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1097/mnh.0000000000001131
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00