Long-term growth hormone effects in Prader-Willi syndrome
GH therapy in PWS significantly improves height and IGF-1 SDS, while relatively decreasing BMI compared to no-GH, indicative of lean mass growth and healthy development. Nonetheless, GH therapy requires careful metabolic monitoring due to its mixed effects on cholesterol and glucose levels.<b>PROSPERO Reg. number: CRD420250649945</b>.
Authors
- Naseem Alyahyawi (ORCID: https://orcid.org/0000-0001-9254-5128)
- Kholoud A Hothan
- Ahlam Mazi (ORCID: https://orcid.org/0000-0003-3125-5260)
- Nour Gazzaz (ORCID: https://orcid.org/0000-0001-5434-4501)
- Esraa Bukhari (ORCID: https://orcid.org/0000-0001-6033-9661)
- Hanaa Hamadallah
- Mahmoud Almutadares
- Nuha Alrayes (ORCID: https://orcid.org/0000-0002-2389-6108)
- Emrah Erkan Mazı (ORCID: https://orcid.org/0000-0003-4879-7584)
- Feyzollah Mansouri (ORCID: https://orcid.org/0000-0002-5316-3220)
Institutions
- King Abdulaziz University (SA)
Publication Details
- Journal
- Saudi Medical Journal
- Published
- 2025-11-01
- DOI
- https://doi.org/10.15537/smj.2025.46.11.20250118
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 0.00