Epidemiology of brachydactyly type A3 in China: a nationwide multicentre population-based study among children aged 3–17 years
This nationwide, multicentre study provides the first national epidemiologic data on BDA3 and associated epiphysial features in Chinese children and adolescents, establishing a prevalence of 10.0%. This baseline supports counselling that a straight, well-functioning short fifth finger is a common anatomic variant and may help reduce unnecessary concern.
Authors
- Jian Geng (ORCID: https://orcid.org/0000-0002-3248-1094)
- Zhenyu Yang (ORCID: https://orcid.org/0000-0002-6916-0016)
- Yandong Liu (ORCID: https://orcid.org/0009-0001-2981-5479)
- Q. F. Zhang (ORCID: https://orcid.org/0009-0004-8124-8426)
- Wenhua Zhao (ORCID: https://orcid.org/0000-0003-4532-0078)
- Glen M. Blake (ORCID: https://orcid.org/0000-0002-1530-5267)
- Fengyun Zhou (ORCID: https://orcid.org/0000-0001-9234-1635)
- Xiaoguang Cheng (ORCID: https://orcid.org/0000-0002-4596-8248)
- Wenshuang Zhang (ORCID: https://orcid.org/0000-0002-9291-2538)
- Ling Wang (ORCID: https://orcid.org/0000-0002-5129-4999)
- Yi Yuan (ORCID: https://orcid.org/0009-0007-7472-0376)
- Qian Zhang (ORCID: https://orcid.org/0000-0003-1077-271X)
- Bo Hu (ORCID: https://orcid.org/0000-0003-0943-5206)
- Yan Dong (ORCID: https://orcid.org/0009-0001-8106-0392)
- Kai Li (ORCID: https://orcid.org/0000-0003-3847-3359)
- Zitong Cheng (ORCID: https://orcid.org/0009-0008-9442-1805)
- Wenhai Wang (ORCID: https://orcid.org/0009-0002-5012-8259)
Institutions
- St Thomas' Hospital (GB)
- Capital Medical University (CN)
- King's College London (GB)
- Chinese Center For Disease Control and Prevention (CN)
- Peking University (CN)
- Beijing Jishuitan Hospital (CN)
- National Center for Clinical Laboratories (CN)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1136/bmjopen-2025-099166
- Primary Topic
- Congenital limb and hand anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Municipal Health Commission