Fibroblast-derived interleukin-11 as a potential biomarker for intestinal fibrostenosis in Crohn’s disease
IL11, mainly derived from fibroblasts, is enriched in fibrostenotic tissue of CD and promotes intestinal fibrosis. IL11 may serve as a potential biomarker for CD fibrostenosis.
Authors
- Jinyu Tan (ORCID: https://orcid.org/0000-0002-8957-0522)
- Ren Mao (ORCID: https://orcid.org/0000-0002-5523-8185)
- Shanshan Xiong (ORCID: https://orcid.org/0000-0003-1229-4600)
- Zishan Liu (ORCID: https://orcid.org/0000-0002-6066-1092)
- Caiguang Liu (ORCID: https://orcid.org/0000-0003-4876-7000)
- Longyuan Zhou (ORCID: https://orcid.org/0000-0002-3057-2566)
- Jie Li (ORCID: https://orcid.org/0000-0003-1232-3248)
- Yu Wang (ORCID: https://orcid.org/0000-0002-5444-5916)
- Weidong Huang (ORCID: https://orcid.org/0000-0002-4455-0632)
- Xiaomin Wu (ORCID: https://orcid.org/0000-0003-3858-7399)
- Minhu Chen (ORCID: https://orcid.org/0000-0001-8181-0846)
- Jing Nie (ORCID: https://orcid.org/0000-0001-5080-6553)
- Jinshen He (ORCID: https://orcid.org/0000-0002-7559-5243)
- Yao Zhang
Institutions
- Sun Yat-sen University (CN)
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Therapeutic Advances in Gastroenterology
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1177/17562848251391093
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82