Ferroptosis-associated RNA-binding proteins predict clinical outcomes in head and neck squamous cell carcinoma
We established the first ferroptosis-associated RBP signature as an independent prognostic biomarker for HNSCC. Beyond prognostic utility, this signature elucidates novel mechanisms linking RBP-mediated ferroptosis to immune evasion in HNSCC, offering therapeutic targets.
Authors
- Guanggang Shi (ORCID: https://orcid.org/0000-0003-4147-5187)
- Zhiyu Zhang (ORCID: https://orcid.org/0000-0001-5499-8011)
- Lei Shi (ORCID: https://orcid.org/0000-0001-9258-9454)
- Ming Liu (ORCID: https://orcid.org/0009-0003-2037-363X)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tcr-2025-733
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00