The relationship of ST6GAL1 with clinicopathological and prognostic factors in breast carcinomas

This research is one of the first studies to use ST6GAL1 in preoperative biopsies of patients not scheduled for neoadjuvant treatment. This study revealed highly significant associations of ST6GAL1 expression with HR, HER2, and molecular subtyping. Future studies are recommended to clarify the possible role of ST6GAL1 in resistance to HR and HER2-targeted and other chemotherapeutic agents in BCs.

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Publication Details

Journal
Saudi Medical Journal
Published
2025-11-01
DOI
https://doi.org/10.15537/smj.2025.46.11.20250422
Primary Topic
Glycosylation and Glycoproteins Research
Type
article
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article

The relationship of ST6GAL1 with clinicopathological and prognostic factors in breast carcinomas

Serden Ay, Tuğba Günler, Ethem Ömeroğlu, Sümeyye Kozacıoğlu et al.
Saudi Medical Journal
Glycosylation and Glycoproteins Research
article

The relationship of ST6GAL1 with clinicopathological and prognostic factors in breast carcinomas

Serden Ay, Tuğba Günler, Ethem Ömeroğlu, Sümeyye Kozacıoğlu, İlknur Küçükosmanoğlu
article en

Abstract

This research is one of the first studies to use ST6GAL1 in preoperative biopsies of patients not scheduled for neoadjuvant treatment. This study revealed highly significant associations of ST6GAL1 expression with HR, HER2, and molecular subtyping. Future studies are recommended to clarify the possible role of ST6GAL1 in resistance to HR and HER2-targeted and other chemotherapeutic agents in BCs.

Saudi Medical JournalVol. 46(11)
Konya Food and Agriculture University (TR), Sağlık Bilimleri Üniversitesi (TR)
Openalex Percentile: Top 68%
Glycosylation and Glycoproteins Research
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