Motor stereotypies, <i>Dhat</i> syndrome, and gaming disorder: A masquerading presentation of Wilson's disease
Wilson's disease, a rare genetic disorder caused by ATP7B gene mutations, disrupts copper metabolism, often presenting with psychiatric symptoms in 20-30% of cases before diagnosis. Diagnostic challenges arise owing to non-specific symptoms, leading to potential misdiagnosis. <i>Dhat</i> syndrome, a culture-bound syndrome prevalent in the Indian subcontinent, involves distress over perceived semen loss and, thus, the loss of vitality. We report a case of a young male with <i>dhat</i> syndrome, asymmetrical hand movements, behavioural changes, and gaming disorder who, after long being treated for functional neurological disorder, was later diagnosed with Wilson's disease after a comprehensive evaluation.
Authors
- Rakesh Kumar Chadda (ORCID: https://orcid.org/0000-0002-1664-5968)
- Divya Madathiparambil Radhakrishnan (ORCID: https://orcid.org/0000-0002-0641-7398)
- Omar Afroz (ORCID: https://orcid.org/0009-0001-8303-8260)
- Romil Saini (ORCID: https://orcid.org/0000-0001-9553-2349)
- Koushik Sinha Deb (ORCID: https://orcid.org/0000-0001-9546-9036)
- Raja Babu Ramawat (ORCID: https://orcid.org/0000-0002-3719-3438)
Institutions
- Amrita Institute of Medical Sciences and Research Centre (IN)
- Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
- Asian Institute of Medical Sciences (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Tropical Doctor
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1177/00494755251396674
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00