Gene expression changes in male germ cells differ following in vivo versus in vitro exposure to hyperthermia

These results have provided new insight into the molecular basis of male germ cell heat sensitivity, with implications for fertility preservation under environmental or occupational heat exposure. Understanding the dependence of transcriptional responses on the testicular microenvironment could guide future interventions to protect spermatogenesis and inform assisted conception in humans and livestock.

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Publication Details

Journal
Reproduction Fertility and Development
Published
2025-11-20
DOI
https://doi.org/10.1071/rd25066
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
0.00
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article

Gene expression changes in male germ cells differ following in vivo versus in vitro exposure to hyperthermia

Jacob Netherton, G. Tennant, Mark A. Baker, Benjamin R. Robinson et al.
Reproduction Fertility and Development
Sperm and Testicular Function
article

Gene expression changes in male germ cells differ following in vivo versus in vitro exposure to hyperthermia

Jacob Netherton, G. Tennant, Mark A. Baker, Benjamin R. Robinson, G. Williams, Rachel A. Ogle
article en

Abstract

These results have provided new insight into the molecular basis of male germ cell heat sensitivity, with implications for fertility preservation under environmental or occupational heat exposure. Understanding the dependence of transcriptional responses on the testicular microenvironment could guide future interventions to protect spermatogenesis and inform assisted conception in humans and livestock.

Reproduction Fertility and DevelopmentVol. 37(17)
University of Newcastle Australia (AU)
Openalex Percentile: Top 55%
Sperm and Testicular Function
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