Andexanet Alfa in Emergency Cranial Neurosurgical Procedures: A Bicentric Analysis of Efficacy and Safety
Our findings suggest that andexanet alfa is highly effective in preventing secondary bleeding during neurosurgery in patients on factor Xa inhibitors. However, the risk for ischemic events must be carefully considered.
Authors
- Jonas Jelinek
- Shadi Al–Afif (ORCID: https://orcid.org/0000-0002-3213-2142)
- Chiara Negwer (ORCID: https://orcid.org/0000-0003-2997-969X)
- Carolin Albrecht (ORCID: https://orcid.org/0009-0004-8148-1033)
- Omar Abu-Fares (ORCID: https://orcid.org/0000-0002-7466-7014)
- Florian Wild (ORCID: https://orcid.org/0000-0002-0185-1304)
- Manolis Polemikos (ORCID: https://orcid.org/0000-0002-4826-8693)
- Harold F. Hounchonou (ORCID: https://orcid.org/0000-0001-7976-7113)
- Bernhard Meyer (ORCID: https://orcid.org/0000-0002-2846-8719)
- J Krauß
Institutions
- TUM Klinikum (DE)
- Medizinische Hochschule Hannover (DE)
- Hannover Re (Germany) (DE)
Publication Details
- Journal
- Neurocritical Care
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1007/s12028-025-02393-z
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00