Revisiting Glomerulopathy in Clusterin Knockout Mice: A Mouse Model of Human Immunotactoid Glomerulopathy
Our data confirm that the glomerulopathy in CLU-KO B6 mice was similar to the pathological features of ITG and may therefore be considered as an experimental model of ITG. Further, CLU may negatively regulate the fibrillogenesis of ITG.
Authors
- Caigan Du (ORCID: https://orcid.org/0000-0001-8605-5501)
- Changhong Wu (ORCID: https://orcid.org/0000-0002-3128-5075)
- Xinglan Li (ORCID: https://orcid.org/0000-0001-9927-0091)
- Xingwei Cai
- Junya Tan
- Xudan Yang
- Qiunong Guan
Institutions
- University of British Columbia (CA)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Ningbo No. 2 Hospital (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
- First Affiliated Hospital of Chengdu Medical College (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Nephrology
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1111/nep.70150
- Primary Topic
- Clusterin in disease pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00