Sublingual immunotherapy suppresses Th2-type immune response in the allergic rhinitis mouse model by inhibiting the activation of the NFκB pathway
Collectively, we demonstrated that SLIT inhibits NFκB pathway activation, thereby suppressing the Th2-type immune response and alleviating AR progression. These findings provide new insights into the mechanism of SLIT in the treatment of AR.
Authors
- Gan Wang (ORCID: https://orcid.org/0000-0001-7142-4415)
- Zhiling Chen (ORCID: https://orcid.org/0009-0000-3140-4591)
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Immunotherapy
- Published
- 2025-11-02
- DOI
- https://doi.org/10.1080/1750743x.2025.2590477
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00