Harmonizing Iron Terminology and Nomenclature

Iron is indispensable to human physiology, yet its terminology remains fragmented across clinical, laboratory, and chemical fields. With recent updates from several clinical guidelines, a unified framework for iron nomenclature has emerged. This editorial advocates for harmonization, replacing outdated and inconsistent terms such as functional iron deficiency and ferrous/ferric with standardized equivalents like iron-restricted erythropoiesis and iron(II)/iron(III). Consistent terminology is not a matter of semantics but of precision, ensuring clarity in communication, comparability across studies, and accuracy in diagnosis. Adoption of a common lexicon will strengthen research interpretation, education, and global clinical practice.

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Publication Details

Journal
Cureus
Published
2025-11-20
DOI
https://doi.org/10.7759/cureus.97362
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
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article

Harmonizing Iron Terminology and Nomenclature

Mohamed Abdallah Yassin, Yousef Hawas, Abdulqadir J. J. Nashwan, Badir Zakir
Cureus
Iron Metabolism and Disorders
article

Harmonizing Iron Terminology and Nomenclature

Mohamed Abdallah Yassin, Yousef Hawas, Abdulqadir J. J. Nashwan, Badir Zakir
article en

Abstract

Iron is indispensable to human physiology, yet its terminology remains fragmented across clinical, laboratory, and chemical fields. With recent updates from several clinical guidelines, a unified framework for iron nomenclature has emerged. This editorial advocates for harmonization, replacing outdated and inconsistent terms such as functional iron deficiency and ferrous/ferric with standardized equivalents like iron-restricted erythropoiesis and iron(II)/iron(III). Consistent terminology is not a matter of semantics but of precision, ensuring clarity in communication, comparability across studies, and accuracy in diagnosis. Adoption of a common lexicon will strengthen research interpretation, education, and global clinical practice.

CureusVol. 17(11)
University of Leicester (GB), Tanta University (EG), National Center for Cancer Care and Research (QA), Hamad Medical Corporation (QA)
Openalex Percentile: Top 54%
Iron Metabolism and Disorders
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