Artificial Intelligence Enhanced Analysis of Coronary CT Angiography to Facilitate Chronic Total Occlusion Percutaneous Coronary Intervention

In patients with chronic total occlusions (CTO), percutaneous coronary intervention (PCI) often has modest success rates unless performed by experienced centers and operators. Coronary computed tomography angiography (CCTA) guidance can enhance the success rates of CTO PCI. Its application, however, is limited due to the lack of expertise among interventional cardiologists in CCTA analysis, logistical barriers, and insufficient multidisciplinary collaboration. This review explores the emerging role of novel artificial intelligence (AI)-based platforms in facilitating CTO detection and pre-procedural CTO PCI planning, which enables interventional cardiologists to perform CCTA analysis without having advanced imaging training. Additionally, we provide a guide on how to use these tools and discuss the future implications of utilizing CCTA for CTO diagnosis and PCI planning.

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Publication Details

Journal
Catheterization and Cardiovascular Interventions
Published
2025-11-20
DOI
https://doi.org/10.1002/ccd.70312
Primary Topic
Coronary Interventions and Diagnostics
Type
article
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article

Artificial Intelligence Enhanced Analysis of Coronary CT Angiography to Facilitate Chronic Total Occlusion Percutaneous Coronary Intervention

Emmanouil S. Brilakis, Bavana V. Rangan, Pedro E P Carvalho, M. Nicholas Burke et al.
Catheterization and Cardiovascular Interventions
Coronary Interventions and Diagnostics
article

Artificial Intelligence Enhanced Analysis of Coronary CT Angiography to Facilitate Chronic Total Occlusion Percutaneous Coronary Intervention

Emmanouil S. Brilakis, Bavana V. Rangan, Pedro E P Carvalho, M. Nicholas Burke, Victor Cheng, João L. Cavalcante, Eleni Kladou, Deniz Mutlu, Lorenzo Azzalini, John R. Lesser, Sandeep Jalli, Dimitrios Strepkos, Michaella Alexandrou, Yader Sandoval
article en

Abstract

In patients with chronic total occlusions (CTO), percutaneous coronary intervention (PCI) often has modest success rates unless performed by experienced centers and operators. Coronary computed tomography angiography (CCTA) guidance can enhance the success rates of CTO PCI. Its application, however, is limited due to the lack of expertise among interventional cardiologists in CCTA analysis, logistical barriers, and insufficient multidisciplinary collaboration. This review explores the emerging role of novel artificial intelligence (AI)-based platforms in facilitating CTO detection and pre-procedural CTO PCI planning, which enables interventional cardiologists to perform CCTA analysis without having advanced imaging training. Additionally, we provide a guide on how to use these tools and discuss the future implications of utilizing CCTA for CTO diagnosis and PCI planning.

Catheterization and Cardiovascular InterventionsVol. 107(1)
Abbott Northwestern Hospital (US), University of Washington (US), Minneapolis Heart Institute Foundation (US)
Openalex Percentile: Top 46%
Coronary Interventions and Diagnostics
DOISourceOpenAlex
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Artificial Intelligence Enhanced Analysis of Coronary CT Angiography to Facilitate Chronic Total Occlusion Percutaneous Coronary Intervention — Emmanouil S. Brilakis, Bavana V. Rangan, et al. · Catheterization and Cardiovascular Interventions (2025) | TGRS Research Map | TGRS