Melioidosis presenting as hepatosplenic abscesses: A case series

Melioidosis, caused by <i>Burkholderia pseudomallei</i>, is an under-recognised tropical infection that often produces visceral abscesses. Hepatosplenic involvement is less commonly described and can mimic pyogenic or tubercular disease and commonly affects patients with diabetes, alcohol use, or immuno-compromised conditions. We report a retrospective series of 10 culture-confirmed patients from a tertiary care centre in India presenting with liver or splenic abscesses diagnosed by imaging and culture. Treatment comprised intravenous meropenem or ceftazidime followed by oral trimethoprim-sulfamethoxazole. Close follow-up is essential to ensure eradication and reduce relapse.

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Publication Details

Journal
Tropical Doctor
Published
2025-11-20
DOI
https://doi.org/10.1177/00494755251395461
Primary Topic
Burkholderia infections and melioidosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Melioidosis presenting as hepatosplenic abscesses: A case series

Dibya Lochan Praharaj, Srikanth Kondapalli, Manoj Kumar Sahu, Suprabhat Giri et al.
Tropical Doctor
Burkholderia infections and melioidosis
article

Melioidosis presenting as hepatosplenic abscesses: A case series

Dibya Lochan Praharaj, Srikanth Kondapalli, Manoj Kumar Sahu, Suprabhat Giri, Anil Chandra Anand, Swati Das
article en

Abstract

Melioidosis, caused by <i>Burkholderia pseudomallei</i>, is an under-recognised tropical infection that often produces visceral abscesses. Hepatosplenic involvement is less commonly described and can mimic pyogenic or tubercular disease and commonly affects patients with diabetes, alcohol use, or immuno-compromised conditions. We report a retrospective series of 10 culture-confirmed patients from a tertiary care centre in India presenting with liver or splenic abscesses diagnosed by imaging and culture. Treatment comprised intravenous meropenem or ceftazidime followed by oral trimethoprim-sulfamethoxazole. Close follow-up is essential to ensure eradication and reduce relapse.

Tropical DoctorVol. 56(2)
Kalinga University (IN), All India Institute of Medical Sciences Bhubaneswar (IN), Institute of Medical Sciences (IN)
Openalex Percentile: Top 54%
Burkholderia infections and melioidosis
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