Downregulation of serum vitamin D receptor level, serum 25-hydroxyvitamin D, and association of vitamin D receptor gene polymorphisms ApaI and TaqI with obesity in the Bangladeshi population

We report the downregulation of serum VDR levels and serum 25-hydroxy vitamin D levels in people with obesity. Moreover, a polymorphism of Apal (rs7975232 C > A) in the VDR gene increases the risk of developing obesity in the Bangladeshi population.

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Journal
PLoS ONE
Published
2025-11-20
DOI
https://doi.org/10.1371/journal.pone.0337523
Primary Topic
Vitamin D Research Studies
Type
article
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article

Downregulation of serum vitamin D receptor level, serum 25-hydroxyvitamin D, and association of vitamin D receptor gene polymorphisms ApaI and TaqI with obesity in the Bangladeshi population

Md. Aminul Haque, Javed Hasan, Sadia Biswas Mumu, Md Shaki Mostaid et al.
PLoS ONE
Vitamin D Research Studies
article

Downregulation of serum vitamin D receptor level, serum 25-hydroxyvitamin D, and association of vitamin D receptor gene polymorphisms ApaI and TaqI with obesity in the Bangladeshi population

Md. Aminul Haque, Javed Hasan, Sadia Biswas Mumu, Md Shaki Mostaid, Muhammed Mahfuzur Rahman, Munira Jahan Raisa, Annur Ferdous, Nafiz Imtiaz Siam, Shatabdy Barua Trisha, Md Hijbullah
article en

Abstract

We report the downregulation of serum VDR levels and serum 25-hydroxy vitamin D levels in people with obesity. Moreover, a polymorphism of Apal (rs7975232 C > A) in the VDR gene increases the risk of developing obesity in the Bangladeshi population.

PLoS ONEVol. 20(11)
North South University (BD), BRAC University (BD)
Openalex Percentile: Top 51%
Vitamin D Research Studies
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