Privileged localisation: Atypical hand–foot–mouth disease at locus minoris resistentiae
Hand, foot, and mouth disease (HFMD) is a common viral illness predominantly affecting children, but atypical presentations can occur, especially in areas of reduced resistance, such as burn scars. We present two cases with atypical HFMD lesions localised to a previously healed scald burn area, with classic lesions on the hands and feet. This unusual presentation highlights the role of immune dysregulation in healed burn scars, predisposing them to infection.
Authors
- Kaliaperumal Karthikeyan (ORCID: https://orcid.org/0009-0004-8275-3889)
- Ariharasudhan Varadharajan (ORCID: https://orcid.org/0009-0006-5730-1949)
- Ramamoorthy Logamoorthy
- Vanila Muthukannu
Institutions
- Sri Manakula Vinayagar Medical College and Hospital (IN)
Publication Details
- Journal
- Tropical Doctor
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1177/00494755251395470
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00