Privileged localisation: Atypical hand–foot–mouth disease at locus minoris resistentiae

Hand, foot, and mouth disease (HFMD) is a common viral illness predominantly affecting children, but atypical presentations can occur, especially in areas of reduced resistance, such as burn scars. We present two cases with atypical HFMD lesions localised to a previously healed scald burn area, with classic lesions on the hands and feet. This unusual presentation highlights the role of immune dysregulation in healed burn scars, predisposing them to infection.

Authors

Institutions

Publication Details

Journal
Tropical Doctor
Published
2025-11-20
DOI
https://doi.org/10.1177/00494755251395470
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Privileged localisation: Atypical hand–foot–mouth disease at locus minoris resistentiae

Kaliaperumal Karthikeyan, Ariharasudhan Varadharajan, Ramamoorthy Logamoorthy, Vanila Muthukannu
Tropical Doctor
Viral Infections and Immunology Research
article

Privileged localisation: Atypical hand–foot–mouth disease at locus minoris resistentiae

Kaliaperumal Karthikeyan, Ariharasudhan Varadharajan, Ramamoorthy Logamoorthy, Vanila Muthukannu
article en

Abstract

Hand, foot, and mouth disease (HFMD) is a common viral illness predominantly affecting children, but atypical presentations can occur, especially in areas of reduced resistance, such as burn scars. We present two cases with atypical HFMD lesions localised to a previously healed scald burn area, with classic lesions on the hands and feet. This unusual presentation highlights the role of immune dysregulation in healed burn scars, predisposing them to infection.

Tropical DoctorVol. 56(2)
Sri Manakula Vinayagar Medical College and Hospital (IN)
Openalex Percentile: Top 47%
Viral Infections and Immunology Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.