Histopathological and Clinical Features of HER2-Positive Breast Cancers across Hormone Receptor Subgroups: A Cross-Sectional Analysis
HER2-positive breast carcinomas show variability by HR status. The HER2-enriched subtype is associated with older age, higher histological grade, and advanced nodal stage, suggesting a more aggressive phenotype. Recognizing these patterns aids in accurate prognostication and guiding individualized therapy.
Authors
- Kanthilatha Pai
- Karthik Udupa (ORCID: https://orcid.org/0000-0002-4906-3972)
- Swathi Prabhu (ORCID: https://orcid.org/0000-0002-0742-5373)
- Anuradha Calicut Kini Rao
- Naurin Kasem
Institutions
- Manipal Academy of Higher Education (IN)
Publication Details
- Journal
- F1000Research
- Published
- 2025-11-13
- DOI
- https://doi.org/10.12688/f1000research.171847.1
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00