Middle meningeal artery embolization for chronic subdural hematoma using PHIL-LV: A case series

BackgroundChronic subdural hematoma (CSDH) is increasingly treated with middle meningeal artery embolization (MMAE). This study evaluated MMAE using a precipitating hydrophobic injectable liquid low viscosity (PHIL-LV) liquid embolic agent under general anaesthesia.MethodsConsecutive patients who underwent MMAE for CSDH with PHIL-LV at a single comprehensive neuroscience centre during a two-year period (2023-2025) were analysed. Patient clinical characteristics, imaging characteristics and procedural characteristics were recorded and described.ResultsTwenty-two patients (mean age 76 ± 13) were included in this study. Mean CSDH size was 18.4 ± 6.7 mm; 9/22 (40.9%) patients had a Charlson Comorbidity index >4. MMA embolization was successful in all 22/22 (100%) patients. Symptomatic improvement was observed in 14/17 (82.4%) of patients. During mean follow up (10.7 ± 9.2 (range 1-36)) weeks, mean reduction in CSDH thickness was 12.1 ± 9.9 mm; 13/16 (81.3%) patients had at least partial radiologic resolution of CSDH. No patients required retreatment.ConclusionPHIL-LV MMAE was safe and effective for treatment of CSDH in this case series.

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Journal
Interventional Neuroradiology
Published
2025-11-20
DOI
https://doi.org/10.1177/15910199251397148
Primary Topic
Neurosurgical Procedures and Complications
Type
article
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article

Middle meningeal artery embolization for chronic subdural hematoma using PHIL-LV: A case series

Stephen Bacchi, Alistair Jukes, Rebecca Scroop, Michael J. Waters et al.
Interventional Neuroradiology
Neurosurgical Procedures and Complications
article

Middle meningeal artery embolization for chronic subdural hematoma using PHIL-LV: A case series

Stephen Bacchi, Alistair Jukes, Rebecca Scroop, Michael J. Waters, Rudy Goh, D. Taylor
article en

Abstract

BackgroundChronic subdural hematoma (CSDH) is increasingly treated with middle meningeal artery embolization (MMAE). This study evaluated MMAE using a precipitating hydrophobic injectable liquid low viscosity (PHIL-LV) liquid embolic agent under general anaesthesia.MethodsConsecutive patients who underwent MMAE for CSDH with PHIL-LV at a single comprehensive neuroscience centre during a two-year period (2023-2025) were analysed. Patient clinical characteristics, imaging characteristics and procedural characteristics were recorded and described.ResultsTwenty-two patients (mean age 76 ± 13) were included in this study. Mean CSDH size was 18.4 ± 6.7 mm; 9/22 (40.9%) patients had a Charlson Comorbidity index >4. MMA embolization was successful in all 22/22 (100%) patients. Symptomatic improvement was observed in 14/17 (82.4%) of patients. During mean follow up (10.7 ± 9.2 (range 1-36)) weeks, mean reduction in CSDH thickness was 12.1 ± 9.9 mm; 13/16 (81.3%) patients had at least partial radiologic resolution of CSDH. No patients required retreatment.ConclusionPHIL-LV MMAE was safe and effective for treatment of CSDH in this case series.

Interventional Neuroradiology
Royal Adelaide Hospital (AU), Harvard University (US), Massachusetts General Hospital (US), The University of Adelaide (AU)
Openalex Percentile: Top 51%
Neurosurgical Procedures and Complications
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