Postprandial Glucagon Metabolism in Healthy and Type 1 Diabetes
This study was conducted to determine postprandial glucagon metabolism in people with and without type 1 diabetes. We wanted to determine the cause for higher early postprandial glucagon concentrations in type 1 diabetes. We found that higher early postprandial glucagon turnover is the cause of higher early postprandial glucagon concentrations in type 1 diabetes Strategies that decrease early post prandial glucagon fluxes could improve postprandial glucose concentrations in type 1 diabetes.
Authors
- Ananda Basu (ORCID: https://orcid.org/0000-0002-1646-9749)
- Akhilesh Pandey (ORCID: https://orcid.org/0000-0001-9943-6127)
- Claudio Cobelli (ORCID: https://orcid.org/0000-0002-0169-6682)
- Rita Basu (ORCID: https://orcid.org/0000-0002-7827-9422)
- Michele Schiavon (ORCID: https://orcid.org/0000-0003-0590-2399)
- FNU RUCHI
- Chiara Dalla Man (ORCID: https://orcid.org/0000-0002-4908-0596)
Institutions
- Mayo Clinic (US)
- University of Padua (IT)
- University of Alabama at Birmingham (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
- University of Virginia (US)
Publication Details
- Journal
- Diabetes
- Published
- 2025-11-20
- DOI
- https://doi.org/10.2337/db25-0587
- Primary Topic
- Diabetes Management and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Vanderbilt University
- Vanderbilt University Medical Center
- Dipartimenti di Eccellenza
- Ministero dell’Istruzione, dell’Università e della Ricerca
- National Institutes of Health
- National Cancer Institute
- National Institute of Diabetes and Digestive and Kidney Diseases