GDF15 is a putative biomarker for distinguishing pulmonary veno-occlusive disease and pulmonary arterial hypertension

Study identifies GDF15 as a biomarker-accurately distinguishing PVOD from other PAH forms and predicting outcomes across PVOD, IPAH, and HPAH-advancing earlier diagnosis and personalized treatment.

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Publication Details

Journal
Journal of Clinical Investigation
Published
2025-11-20
DOI
https://doi.org/10.1172/jci199159
Primary Topic
GDF15 and Related Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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article

GDF15 is a putative biomarker for distinguishing pulmonary veno-occlusive disease and pulmonary arterial hypertension

Luke Howard, Amit Prabhakar, Tin Aung, Steven R. Hays et al.
Journal of Clinical Investigation
GDF15 and Related Biomarkers
article

GDF15 is a putative biomarker for distinguishing pulmonary veno-occlusive disease and pulmonary arterial hypertension

Luke Howard, Amit Prabhakar, Tin Aung, Steven R. Hays, Colin Church, Paul J. Wolters, John R. Greenland, Mark R. Toshner, Jonathan Paul Singer, S. Carter, Stefan Ting Graf, SJ Wort, Prajakta Ghatpande, Jacqueline T. DesJardin, Marc A. Simon, Eckart M. D. D. De Bie, Michael Wax, Akiko Hata, Jasleen Kukreja, Giorgio Lagna, David G. Kiely, Emily Sumpena
article en

Abstract

Study identifies GDF15 as a biomarker-accurately distinguishing PVOD from other PAH forms and predicting outcomes across PVOD, IPAH, and HPAH-advancing earlier diagnosis and personalized treatment.

Journal of Clinical InvestigationVol. 136(2)
Imperial College Healthcare NHS Trust (GB), University of California, San Francisco (US), University of Cambridge (GB), Hammersmith Hospital (GB), Golden Jubilee National Hospital (GB), Royal Brompton Hospital (GB), Lung Institute (US), Sheffield Teaching Hospitals NHS Foundation Trust (GB), Papworth Hospital NHS Foundation Trust (GB), Pulmonary and Allergy Associates (US), Comprehensive Cardiovascular (US), San Francisco VA Health Care System (US), Imperial College London (GB)
National Institute for Health and Care Research, British Heart Foundation, Cambridge Trust, Gates Cambridge Trust, National Institutes of Health
Openalex Percentile: Top 50%
GDF15 and Related Biomarkers
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