Epigenetic alterations in rotator cuff tendinopathy and degenerative cuff tears: a systematic review
Our findings indicate that epigenetic regulation may play an important role in the pathophysiology of RC tendinopathy and degenerative tear and that there is a high potential for epigenetic biomarkers and therapeutics to aid in the diagnosis, prognosis, and treatment of this condition.
Authors
- Peter J. Millett (ORCID: https://orcid.org/0000-0002-8298-3746)
- Dane R.G. Lind (ORCID: https://orcid.org/0000-0003-3379-0961)
- Benjamin B. Rothrauff (ORCID: https://orcid.org/0000-0002-8301-025X)
- Grant J. Dornan (ORCID: https://orcid.org/0000-0001-9039-9163)
- Johnny Huard (ORCID: https://orcid.org/0000-0002-2926-569X)
- Bret Hatzinger (ORCID: https://orcid.org/0009-0006-3591-0487)
- Nick A. Felan (ORCID: https://orcid.org/0009-0009-2100-8224)
Institutions
- Steadman Clinic (US)
- Steadman Philippon Research Institute (US)
Publication Details
- Journal
- JSES Reviews Reports and Techniques
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.xrrt.2025.100618
- Primary Topic
- Shoulder Injury and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00