BlockDrugChain: A blockchain and ML-driven framework for scalable drug discovery management

The discovery of new drugs is a collaborative effort that involves researchers, pharmaceutical companies, and regulators. Cyberattacks, data tampering, and a lack of transparency are all common problems in today's centralised systems. This paper suggests using Hyperledger Fabric-based blockchain technology to increase the efficiency, transparency, and safety of drug discovery. The straightforward user interface makes it easy to upload, update, and validate data. Each contributor is granted a unique ID using SHA-256, which protects the data. With the use of machine learning, data is improved and people are empowered to make better decisions. To expedite verification, critical metadata is stored on-chain, while large files are stored off-chain. Custom smart contracts safeguard your data and transfer ownership to you. According to performance studies, it can process up to 365 transactions per second, making it ideal for large-scale collaboration. An alternative to traditional drug discovery approaches that is both modern and decentralised is offered by this idea.

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Publication Details

Journal
Franklin Open
Published
2025-11-20
DOI
https://doi.org/10.1016/j.fraope.2025.100438
Primary Topic
Blockchain Technology Applications and Security
Type
article
Field-Weighted Citation Impact
0.00
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article

BlockDrugChain: A blockchain and ML-driven framework for scalable drug discovery management

Dileep Kumar Murala
Franklin Open
Blockchain Technology Applications and Security
article

BlockDrugChain: A blockchain and ML-driven framework for scalable drug discovery management

Dileep Kumar Murala
article en

Abstract

The discovery of new drugs is a collaborative effort that involves researchers, pharmaceutical companies, and regulators. Cyberattacks, data tampering, and a lack of transparency are all common problems in today's centralised systems. This paper suggests using Hyperledger Fabric-based blockchain technology to increase the efficiency, transparency, and safety of drug discovery. The straightforward user interface makes it easy to upload, update, and validate data. Each contributor is granted a unique ID using SHA-256, which protects the data. With the use of machine learning, data is improved and people are empowered to make better decisions. To expedite verification, critical metadata is stored on-chain, while large files are stored off-chain. Custom smart contracts safeguard your data and transfer ownership to you. According to performance studies, it can process up to 365 transactions per second, making it ideal for large-scale collaboration. An alternative to traditional drug discovery approaches that is both modern and decentralised is offered by this idea.

Franklin OpenVol. 13
ICFAI Foundation for Higher Education (IN)
Openalex Percentile: Top 51%
Blockchain Technology Applications and Security
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