Primary graft dysfunction in donor after brain death vs normothermic regional perfusion heart transplants

After adjustment for demographics and clinical characteristics, NRP was associated with higher risk of PGD vs DBD. While index hospitalization resource utilization was increased for PGD patients, midterm outcomes were not different. Further studies are warranted to understand characteristics of NRP that may be associated with increased PGD risk and the clinical significance of PGD post-NRP.

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Publication Details

Journal
JHLT Open
Published
2025-11-20
DOI
https://doi.org/10.1016/j.jhlto.2025.100439
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Primary graft dysfunction in donor after brain death vs normothermic regional perfusion heart transplants

Amanda Topik, Jade Kozuch, Victor Pretorius, Justin Cole et al.
JHLT Open
Transplantation: Methods and Outcomes
article

Primary graft dysfunction in donor after brain death vs normothermic regional perfusion heart transplants

Amanda Topik, Jade Kozuch, Victor Pretorius, Justin Cole, Melissa J. Philbrick, M. Mariski, Kimberly N. Hong, Marcus A. Urey, Fadi Azar, Melissa Vu Maffei, Mark J. Kearns
article en

Abstract

After adjustment for demographics and clinical characteristics, NRP was associated with higher risk of PGD vs DBD. While index hospitalization resource utilization was increased for PGD patients, midterm outcomes were not different. Further studies are warranted to understand characteristics of NRP that may be associated with increased PGD risk and the clinical significance of PGD post-NRP.

JHLT OpenVol. 11
University of California San Diego (US)
Openalex Percentile: Top 46%
Transplantation: Methods and Outcomes
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