A pooled primate screen finds that MYD88-CD40 boosts CAR-T

suppressor cells 9 ) and are critical in the mode of action of approved drugs (eg, NK cells in the context of anti-CD38 monoclonal antibodies 10 ).Finally, to define the methods and create userfriendly tools for standardized and routine assessment of immune age in routine practice.The authors should be commended for taking the first step in such a relevant patient population!Conflict-of-interest disclosure: B.P.

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Publication Details

Journal
Blood
Published
2025-11-20
DOI
https://doi.org/10.1182/blood.2025030745
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00

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article

A pooled primate screen finds that MYD88-CD40 boosts CAR-T

Mark B. Leick
Blood
CAR-T cell therapy research
article

A pooled primate screen finds that MYD88-CD40 boosts CAR-T

Mark B. Leick
article en

Abstract

suppressor cells 9 ) and are critical in the mode of action of approved drugs (eg, NK cells in the context of anti-CD38 monoclonal antibodies 10 ).Finally, to define the methods and create userfriendly tools for standardized and routine assessment of immune age in routine practice.The authors should be commended for taking the first step in such a relevant patient population!Conflict-of-interest disclosure: B.P.

BloodVol. 146(21)
Massachusetts General Hospital (US)
Amgen, Bristol-Myers Squibb, GlaxoSmithKline, Sanofi, Gilead Sciences, Celgene
Openalex Percentile: Top 52%
CAR-T cell therapy research
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A pooled primate screen finds that MYD88-CD40 boosts CAR-T — Mark B. Leick · Blood (2025) | TGRS Research Map | TGRS