Application of functional magnetic resonance imaging in identifying responsible brain regions associated with spinal diseases related pain

Resting-state brain fMRI indicates a cerebello-thalamo-cortical alteration pattern in spinal diseases related pain featuring cerebellar involvement, prefrontal subspecialization, and multilevel sensorimotor disruption. These cross-sectional associations may inform hypothesis-generation for future neuromodulation studies and provide candidate biomarkers for monitoring, pending prospective validation.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-11-20
DOI
https://doi.org/10.3389/fmed.2025.1585799
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Application of functional magnetic resonance imaging in identifying responsible brain regions associated with spinal diseases related pain

Yuehuan Zheng, Lemeng Ren, Junpeng Zhang, Jing Zhang et al.
Frontiers in Medicine
Pain Mechanisms and Treatments
article

Application of functional magnetic resonance imaging in identifying responsible brain regions associated with spinal diseases related pain

Yuehuan Zheng, Lemeng Ren, Junpeng Zhang, Jing Zhang, Xiaopei Sun, Nannan Wang
article en

Abstract

Resting-state brain fMRI indicates a cerebello-thalamo-cortical alteration pattern in spinal diseases related pain featuring cerebellar involvement, prefrontal subspecialization, and multilevel sensorimotor disruption. These cross-sectional associations may inform hypothesis-generation for future neuromodulation studies and provide candidate biomarkers for monitoring, pending prospective validation.

Frontiers in MedicineVol. 12
Shanghai Jiao Tong University (CN), Ruijin Hospital (CN), Shanghai University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 56%
Pain Mechanisms and Treatments
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Application of functional magnetic resonance imaging in identifying responsible brain regions associated with spinal diseases related pain — Yuehuan Zheng, Lemeng Ren, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS